There is a workaround for mayo-based casseroles
There is a bit of a solution: You can freeze everything except the mayonnaise and add it later. Be aware that mayonnaise might be included in your store-bought salad dressing, so check the ingredients before preparing any casserole that uses a creamy dressing. If you're making a dish where mayonnaise is a key ingredient (like a spinach and artichoke casserole, which typically combines cream cheese and mayo), you can still prepare most components in advance.
Cook the pasta, meat, vegetables, and any other ingredients that freeze well ahead of time. Then, store everything in an airtight container or dish as you would if it were fully cooked. When you're ready to defrost, that's the perfect time to prepare the mayonnaise mixture that will likely bind the casserole together. While this method may not be ideal for last-minute meals, it’s a great option for planning ahead for holidays or gatherings. You can purchase all the ingredients at once and prepare most of them in advance, then simply assemble the casserole when you're ready to bake and serve.
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